Description

3-Bromo-5-Fluoro-2-Methoxyphenol is a high-purity, halogenated phenolic compound serving as a critical building block in advanced organic synthesis. Its unique molecular structure, featuring bromine and fluorine substituents on a methoxyphenol core, makes it a versatile intermediate for creating complex molecules with tailored properties. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, where the bromo-fluoro substitution pattern can enhance biological activity and environmental stability.
• Material Science Precursor: Employed in the synthesis of specialty polymers, liquid crystals, and organic electronic materials that require halogenated aromatic units for specific electronic or physical characteristics.
• Chemical Research & Development: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and in organic methodology development for new coupling and functionalization reactions.
• Dye and Pigment Intermediate: Acts as a starting material for synthesizing complex halogenated dyes and pigments, contributing to color fastness and unique spectral properties.

Basic Information

Product Name	3-Bromo-5-Fluoro-2-Methoxyphenol
CAS No.	1026796-60-0
Molecular Formula	C7H6BrFO2
Molecular Weight	221.03 g/mol
Synonyms	2-Methoxy-3-bromo-5-fluorophenol; 5-Fluoro-3-bromo-2-methoxyphenol; 3-Bromo-5-fluoro-2-methoxy-phenol; 2-Bromo-6-fluoro-3-methoxyphenol; Phenol, 3-bromo-5-fluoro-2-methoxy-; 3-Bromo-5-fluoro-guaiacol
EINECS	Contact for details

Quality Control

Every batch of 3-Bromo-5-Fluoro-2-Methoxyphenol is manufactured under strict quality management systems and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. Our products are developed to meet the stringent requirements of research and cGMP-grade production environments. A detailed Certificate of Analysis (COA) providing specifications for identity (IR, NMR), purity (HPLC), and related substances is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.