Description

3-Fluoro-4-(4-Propylpiperazin-1-Yl)Aniline is a high-value fluorinated aniline derivative featuring a propylpiperazine substituent, serving as a critical advanced intermediate in modern organic synthesis. Its molecular architecture makes it indispensable for constructing complex pharmacophores, particularly in the development of targeted small-molecule therapeutics. This compound is primarily sought by research institutions and pharmaceutical companies engaged in medicinal chemistry, agrochemical research, and the synthesis of specialty fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially in oncology and central nervous system (CNS) therapeutic areas.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and library synthesis for high-throughput screening.
• Agrochemical Development: Intermediate in the creation of new-generation herbicides and pesticides with improved efficacy.
• Ligand Synthesis: Precursor for chelating agents and catalysts used in asymmetric synthesis and metal-organic frameworks (MOFs).
• Fine Chemical Production: Employed in the multi-step synthesis of complex, high-value specialty chemicals and dyes.
• Bioconjugation: The aniline group can be utilized for coupling reactions in the development of antibody-drug conjugates (ADCs) or diagnostic probes.

Basic Information

Product Name	3-Fluoro-4-(4-Propylpiperazin-1-Yl)Aniline
CAS No.	1026156-06-8
Molecular Formula	C13H20FN3
Molecular Weight	237.32 g/mol
Synonyms	1-(2-Fluoro-4-aminophenyl)-4-propylpiperazine; 4-(4-Propylpiperazin-1-yl)-3-fluoroaniline; 3-Fluoro-4-(4-propyl-1-piperazinyl)aniline; 3-Fluoro-4-(4-n-propylpiperazin-1-yl)aniline; Benzenamine, 3-fluoro-4-(4-propyl-1-piperazinyl)-; 1026156-06-8; FC-1034 (Potential Research Code)
EINECS	Contact for details

Quality Control

Our 3-Fluoro-4-(4-Propylpiperazin-1-Yl)Aniline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications. Our quality commitment supports applications in cGMP and ISO-regulated environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is easily oxidized and should be stored under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.