Description

2-(Dansylsulfonamido)Ethyl-3-(n-Sulfosuccinimidylcarboxy)Ethyl Disulfide, Sodium Salt is a heterobifunctional crosslinking reagent designed for advanced bioconjugation and labeling applications. This compound is engineered to enable the specific and efficient coupling of biomolecules, such as proteins and peptides, to fluorescent dansyl probes for detection and analysis. It is an essential tool for researchers and manufacturers in pharmaceutical development, diagnostic assay production, and proteomics research, where precise and stable labeling is critical.

Application

• Bioconjugation and Protein Labeling: Primary reagent for covalently attaching fluorescent dansyl tags to proteins, antibodies, and peptides for detection and tracking.
• Diagnostic Kit Development: Used in the manufacturing of fluorescent immunoassays (FIAs) and other diagnostic test components.
• Proteomics and Biomarker Research: Facilitates the study of protein-protein interactions, cellular localization, and post-translational modifications via fluorescent tagging.
• Biopharmaceutical Analysis: Employed in the characterization and quality control of therapeutic proteins, including antibody-drug conjugates (ADCs).
• Cell Biology and Imaging: Aids in the fluorescent labeling of cellular components for microscopy and flow cytometry applications.
• Material Science for Biosensors: Used to functionalize surfaces and nanomaterials with specific biomolecules for sensor development.

Basic Information

Product Name	2-(Dansylsulfonamido)Ethyl-3-(n-Sulfosuccinimidylcarboxy)Ethyl Disulfide, Sodium Salt
CAS No.	1024168-37-3
Molecular Formula	C27H34N4NaO10S3
Molecular Weight	693.75 g/mol
Synonyms	Dansyl-SS-NHS; Sodium 2-({5-[(Dimethylamino)naphthalen-1-yl]sulfonyl}amino)ethyl 3-({2,5-dioxopyrrolidin-1-yl}oxy)-3-oxopropyl disulfide; Dansyl C2-SS-NHS ester; N-Sulfosuccinimidyl 2-({5-[(dimethylamino)naphthalen-1-yl]sulfonyl}amino)ethyl 3-({2,5-dioxopyrrolidin-1-yl}oxy)-3-oxopropyl disulfide; Heterobifunctional Dansyl Crosslinker; Dansyl Labeling Reagent; 1024168-37-3; Dansyl sulfosuccinimidyl ester disulfide
EINECS	Contact for details

Quality Control

Our production of 2-(Dansylsulfonamido)Ethyl-3-(n-Sulfosuccinimidylcarboxy)Ethyl Disulfide, Sodium Salt adheres to stringent quality protocols to ensure batch-to-batch consistency and performance reliability for sensitive research and diagnostic applications. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry to verify identity, purity, and functional integrity. Comprehensive Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake. For long-term storage, keep under inert atmosphere.

Specification

Item	Specification
Appearance	Yellow to orange powder or solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 2.0%
Solubility	Soluble in DMSO, DMF; slightly soluble in water
Functional Activity	Tested in standard conjugation assay

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.