Description

2,5-Difluoro-4-Methoxyphenol is a fluorinated phenolic compound with a methoxy substituent, serving as a versatile and valuable building block in advanced organic synthesis. Its unique structure, featuring electron-withdrawing fluorine atoms and an electron-donating methoxy group, makes it a critical intermediate for constructing complex molecules with tailored electronic and steric properties. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), especially in fluorinated drug candidates targeting CNS disorders, oncology, and anti-infectives.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and pesticides, where the difluorophenol moiety can enhance bioavailability and metabolic stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated aromatic cores in electronic materials, contributing to improved thermal stability, dielectric anisotropy, and luminescent properties.
• Polymer Chemistry: Acts as a monomer or modifier in the synthesis of high-performance polymers, such as polyarylates and polyethers, for engineering plastics and specialty coatings.
• Chemical Research & Development: Employed in academic and industrial R&D for exploring new reaction pathways, catalysis, and as a standard for analytical method development.

Basic Information

Product Name	2,5-Difluoro-4-Methoxyphenol
CAS No.	1024068-86-7
Molecular Formula	C7H6F2O2
Molecular Weight	160.12 g/mol
Synonyms	4-Methoxy-2,5-difluorophenol; 2,5-Difluoro-4-methoxy-1-hydroxybenzene; 1-Hydroxy-2,5-difluoro-4-methoxybenzene; 2,5-Difluoro-4-hydroxyanisole; 2,5-Difluoro-4-methoxyphenol; 4-Methoxy-2,5-difluoro-1-phenol; Phenol, 2,5-difluoro-4-methoxy-
EINECS	Contact for details

Quality Control

Our 2,5-Difluoro-4-Methoxyphenol is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is subjected to comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to confirm identity and purity. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes. We support cGMP standards for pharmaceutical applications and can accommodate custom purity specifications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, the container should be opaque or stored in dark conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.