Description

5-Chloro-2-(Methylthio)Pyrimidine-4-Carbonitrile is a versatile and high-value pyrimidine derivative, serving as a critical building block in advanced organic synthesis. Its molecular structure, featuring chloro, methylthio, and cyano functional groups, makes it an essential intermediate for constructing complex heterocyclic systems. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries to develop new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, leveraging its heterocyclic core.
• Material Science Research: Serves as a precursor for the synthesis of functionalized pyrimidines used in organic electronic materials.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	5-Chloro-2-(Methylthio)Pyrimidine-4-Carbonitrile
CAS No.	1023814-07-4
Molecular Formula	C6H4ClN3S
Molecular Weight	185.63 g/mol
Synonyms	4-Cyano-5-chloro-2-(methylthio)pyrimidine; 5-Chloro-2-methylsulfanylpyrimidine-4-carbonitrile; 2-(Methylthio)-5-chloropyrimidine-4-carbonitrile; 5-Chloro-2-(methylmercapto)pyrimidine-4-carbonitrile; 1023814-07-4; 5-Chloro-2-methylthiopyrimidine-4-carbonitrile
EINECS	Contact for details

Quality Control

Our 5-Chloro-2-(Methylthio)Pyrimidine-4-Carbonitrile is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request, supporting your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.