Description

5-Amino-6-Chloro-2-Methylpyrimidine-4-Thiol is a versatile heterocyclic building block and key synthetic intermediate. This compound matters for its role in constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients and agrochemicals. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for synthesizing novel compounds and fine-tuning material properties.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly for antiviral, anticancer, and antimicrobial agents.
• Agrochemical Synthesis: Used in the development of advanced pesticides, herbicides, and fungicides due to its bioactive pyrimidine-thiol core.
• Chemical Research & Development: Serves as a fundamental building block in organic synthesis for creating libraries of heterocyclic compounds.
• Material Science: Potential applications in the development of specialty polymers, ligands for metal complexes, and advanced organic materials.
• Bioconjugation & Probe Development: The reactive thiol and amino groups make it suitable for creating biochemical probes and conjugation linkers.

Basic Information

Product Name	5-Amino-6-Chloro-2-Methylpyrimidine-4-Thiol
CAS No.	1023758-31-7
Molecular Formula	C5H6ClN3S
Molecular Weight	175.64 g/mol
Synonyms	5-Amino-6-chloro-2-methyl-4-pyrimidinethiol; 6-Chloro-2-methyl-4-pyrimidinethiol-5-amine; 4-Pyrimidinethiol, 5-amino-6-chloro-2-methyl-; 2-Methyl-5-amino-6-chloro-4-pyrimidinethiol; 5-Amino-6-chloro-2-methylpyrimidine-4-thione (tautomer); 6-Chloro-2-methyl-4-mercaptopyrimidin-5-amine; ACPT (abbreviation)
EINECS	Contact for details

Quality Control

Our 5-Amino-6-Chloro-2-Methylpyrimidine-4-Thiol is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Due to its light-sensitive nature and tendency to be easily oxidized, it is recommended to handle under an inert atmosphere for long-term storage and to minimize headspace in opened containers.

Specification

Item	Specification
Appearance	White to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.