Description

tert-Butyl 2-(2-Fluoro-3-Hydroxy-6-Nitrophenyl)-3-Oxobutanoate is a high-value, multifunctional chemical intermediate characterized by its unique phenyl ring substitution pattern. This compound is essential for advanced organic synthesis, particularly in constructing complex molecular architectures where precise functional group manipulation is required. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, especially those targeting central nervous system (CNS) disorders or anti-inflammatory pathways.
• Agrochemical Research: Used in developing advanced herbicides and pesticides, where the fluorine and nitro groups contribute to biological activity and metabolic stability.
• Material Science Precursor: Serves as a monomer or functionalizing agent in the creation of specialty polymers and advanced organic materials.
• Dye and Pigment Synthesis: The nitro and hydroxy groups make it a valuable intermediate for producing specialized azo dyes and colorants.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological development and exploring new chemical reactions.
• Fluorine Chemistry Studies: Acts as a model substrate for investigating the effects of fluorine substitution on aromatic reactivity and physical properties.

Basic Information

Product Name	tert-Butyl 2-(2-Fluoro-3-Hydroxy-6-Nitrophenyl)-3-Oxobutanoate
CAS No.	1022112-27-1
Molecular Formula	C₁₄H₁₆FNO₆
Molecular Weight	313.28 g/mol
Synonyms	2-(2-Fluoro-3-hydroxy-6-nitrophenyl)-3-oxobutanoic acid tert-butyl ester; tert-Butyl 2-(2-fluoro-3-hydroxy-6-nitrophenyl)-3-oxobutanoate; 3-Oxobutanoic acid, 2-(2-fluoro-3-hydroxy-6-nitrophenyl)-, 1,1-dimethylethyl ester; 1022112-27-1; Butanoic acid, 2-(2-fluoro-3-hydroxy-6-nitrophenyl)-3-oxo-, 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our production of tert-Butyl 2-(2-Fluoro-3-Hydroxy-6-Nitrophenyl)-3-Oxobutanoate adheres to stringent quality management protocols to ensure batch-to-batch consistency and purity. Each lot is analyzed using advanced chromatographic and spectroscopic techniques. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided and can be tailored to meet specific client or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The compound should be kept under an inert atmosphere if long-term storage is required to prevent potential degradation. Keep away from strong oxidizing agents and bases.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.