Description

H-D-Pro-Pro-Glu-Nh CAS NO 1021646-82-1 is a synthetic peptide derivative, specifically a tripeptide amide, designed for advanced research and development applications. This compound serves as a critical building block and reference standard in the development of novel pharmaceutical agents and biochemical tools. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and life sciences sectors for peptide synthesis, drug discovery, and biochemical studies.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of more complex peptide-based drug candidates targeting various therapeutic areas.
• Biochemical Research: Used as a reference standard or substrate in enzymatic studies and proteomics research to understand biological pathways.
• Drug Discovery: Employed in high-throughput screening (HTS) assays and structure-activity relationship (SAR) studies to identify and optimize new active compounds.
• Peptide Synthesis: Acts as a protected fragment in solid-phase or solution-phase peptide synthesis (SPPS) for constructing longer peptide sequences.
• Academic Research: Utilized in university and institutional laboratories for fundamental studies in medicinal chemistry and peptide science.
• API Development: Supports the development and scale-up processes for Active Pharmaceutical Ingredients (APIs) with specific chiral and structural requirements.

Basic Information

Item	Detail
Product Name	H-D-Pro-Pro-Glu-Nh
CAS No.	1021646-82-1
Molecular Formula	C16H25N5O6
Molecular Weight	383.40 g/mol
Synonyms	H-D-Pro-Pro-Glu-NH2; D-Pro-Pro-Glutamine; (2S)-2-[[(2S)-1-[(2S)-2-Pyrrolidinecarbonyl]pyrrolidine-2-carbonyl]amino]-5-amino-5-oxopentanoic acid; D-Prolyl-D-prolyl-L-glutamine; D-Pro-D-Pro-Gln; DPPG; 1021646-82-1; Boc-D-Pro-Pro-Glu-NH2 (protected form)
EINECS	Contact for details

Quality Control

Our H-D-Pro-Pro-Glu-Nh is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis to confirm stereochemical integrity, and mass spectrometry for identity confirmation. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, ensuring compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.