Description

(3-Fluoro-4-Methyl-Phenyl)-Methyl-Amine is a versatile fluorinated aromatic amine building block of significant interest in advanced organic synthesis. Its core value lies in the strategic combination of a reactive primary amine group with fluorine and methyl substituents on the phenyl ring, enabling precise modulation of electronic and steric properties in target molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it serves as a key intermediate for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of fluorinated drug candidates targeting CNS disorders, oncology, and inflammation.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine atom enhances biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of fluorinated polymers, liquid crystals, and electronic materials to fine-tune thermal and optical properties.
• Chemical Biology Probes: Utilized in the design of molecular probes and fluorescent tags for studying biological systems and diagnostic applications.
• Custom Synthesis & Contract Manufacturing: A high-value starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global life sciences market.

Basic Information

Product Name	(3-Fluoro-4-Methyl-Phenyl)-Methyl-Amine
CAS No.	1021144-10-4
Molecular Formula	C8H10FN
Molecular Weight	139.17 g/mol
Synonyms	1-(3-Fluoro-4-methylphenyl)methanamine; Benzenemethanamine, 3-fluoro-4-methyl-; 3-Fluoro-4-methylbenzylamine; (3-Fluoro-4-methylphenyl)methanamine; 4-Methyl-3-fluorobenzylamine; 3-Fluoro-p-tolylmethylamine; 3-Fluoro-4-methyl-benzylamine; 3-Fluoro-4-methylbenzyl amine
EINECS	Contact for details

Quality Control

Our (3-Fluoro-4-Methyl-Phenyl)-Methyl-Amine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where required, ensuring reliable supply and consistent quality for your most demanding R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This amine is hygroscopic (moisture-sensitive) and should be kept under an inert atmosphere (e.g., nitrogen) for long-term storage to prevent oxidation and degradation. Keep away from strong acids, strong oxidizers, and acyl chlorides.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.