Description

1-(2,4-Difluorophenyl)Butan-1-Amine is a specialized organic amine building block featuring a fluorinated aromatic ring system. This compound is valued for its role as a key chiral intermediate in the synthesis of complex active pharmaceutical ingredients (APIs) and advanced agrochemicals. It is primarily utilized by research and development chemists and process scale-up teams in the pharmaceutical, agrochemical, and fine chemical industries seeking to introduce specific fluorinated motifs into target molecules.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the development of novel drug candidates, particularly in central nervous system (CNS) and anti-infective therapeutic areas.
• Agrochemical Synthesis: Used in the production of advanced herbicides and fungicides where the difluorophenyl group enhances biological activity and environmental stability.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands used in asymmetric catalysis, enabling the synthesis of enantiomerically pure compounds.
• Material Science Research: Employed in the development of specialty polymers and advanced organic materials with tailored properties.
• Custom Synthesis & Contract Manufacturing: A high-purity starting material for custom synthesis projects and scale-up production under cGMP conditions.

Basic Information

Product Name	1-(2,4-Difluorophenyl)Butan-1-Amine
CAS No.	1021033-54-4
Molecular Formula	C10H13F2N
Molecular Weight	185.21 g/mol
Synonyms	1-(2,4-Difluorophenyl)butan-1-amine; 2,4-Difluoro-α-propylbenzylamine; Butan-1-amine, 1-(2,4-difluorophenyl)-; 1-(2,4-Difluorophenyl)-1-butanamine; (2,4-Difluorophenyl)(propyl)methanamine; α-Propyl-2,4-difluorobenzylamine; 1021033-54-4 (CAS Registry Number)
EINECS	Contact for details

Quality Control

Our 1-(2,4-Difluorophenyl)Butan-1-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment by HPLC, to ensure compliance with exacting customer specifications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment, supporting development and regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.