Description

1-(2,4,6-Trifluorophenyl)Ethan-1-Amine is a high-purity fluorinated aromatic amine building block, essential for advanced organic synthesis. Its trifluoromethylphenyl core provides unique electronic and steric properties, making it a critical intermediate for developing novel active pharmaceutical ingredients (APIs) and agrochemicals. This compound is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of drug candidates, particularly in central nervous system (CNS) and anti-infective therapeutic areas.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides where the fluorine atoms enhance bioavailability and metabolic stability.
• Ligand & Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the creation of novel fluorinated polymers and advanced organic electronic materials.
• Chemical Biology Probes: Useful for synthesizing fluorinated probes and tags for imaging and diagnostic applications.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	1-(2,4,6-Trifluorophenyl)Ethan-1-Amine
CAS No.	1021016-20-5
Molecular Formula	C8H8F3N
Molecular Weight	175.15 g/mol
Synonyms	1-(2,4,6-Trifluorophenyl)ethanamine; α-Methyl-2,4,6-trifluorobenzeneethanamine; 1-(2,4,6-Trifluorophenyl)ethylamine; 2,4,6-Trifluoro-α-methylbenzylamine; 1-Aminoethyl-2,4,6-trifluorobenzene; (2,4,6-Trifluorophenyl)ethanamine; 1-(2,4,6-Trifluorophenyl)ethan-1-amine
EINECS	Contact for details

Quality Control

Our 1-(2,4,6-Trifluorophenyl)Ethan-1-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP guidelines where applicable, ensuring consistency and reliability for your most demanding synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.