Description

1-(2-Bromo-5-(Trifluoromethyl)Phenyl)Ethanamine is a high-value, multi-functional aromatic amine building block featuring both bromo and trifluoromethyl substituents, which are critical for modulating the electronic and steric properties of target molecules. This compound is essential for advanced organic synthesis, particularly in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating compounds with enhanced bioactivity and metabolic stability.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of drug candidates, especially those targeting central nervous system (CNS) disorders, oncology, and inflammatory diseases.
• Agrochemical Synthesis: Used to construct advanced herbicides, fungicides, and insecticides where the trifluoromethyl group improves lipophilicity and biological activity.
• Ligand & Catalyst Development: Serves as a starting material for creating novel ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the development of organic electronic materials, such as charge-transport layers or fluorinated polymers.
• Custom Synthesis & Contract Manufacturing: A critical building block for custom synthesis houses serving the life sciences sector.
• Chemical Biology Probes: Used to create tagged molecules for studying biological pathways and target engagement.

Basic Information

Product Name	1-(2-Bromo-5-(Trifluoromethyl)Phenyl)Ethanamine
CAS No.	1020989-57-4
Molecular Formula	C9H7BrF3N
Molecular Weight	266.06 g/mol
Synonyms	1-(2-Bromo-5-(trifluoromethyl)phenyl)ethan-1-amine; 1-(2-Bromo-alpha,alpha,α-trifluoro-p-tolyl)ethylamine; α-Methyl-2-bromo-5-(trifluoromethyl)benzylamine; 2-Bromo-5-(trifluoromethyl)phenethylamine, α-methyl-; 1-(2-Bromo-5-(trifluoromethyl)phenyl)ethanamine hydrochloride (salt form); 2-Bromo-5-trifluoromethylphenethylamine, N-methyl-; [2-Bromo-5-(trifluoromethyl)phenyl]ethanamine
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for advanced intermediates. Every batch is characterized by HPLC, GC, NMR, and mass spectrometry to confirm identity and purity. Certificates of Analysis (COA) are provided with each shipment, detailing all critical parameters. We adhere to cGMP principles where applicable to support our customers' regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.