Description

Ethyl 6-Oxo-2,3,4,6-Tetrahydro-1H-Pyrido[1,2-A]Pyrimidine-9-Carboxylate is a high-purity, advanced pharmaceutical intermediate belonging to the fused pyrimidine class of heterocyclic compounds. This compound serves as a critical building block in modern medicinal chemistry, enabling the synthesis of novel drug candidates with targeted biological activity. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic agents.

Application

• Pharmaceutical Intermediate: Key synthetic precursor for the research and development of new active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and oncology therapeutic areas.
• Medicinal Chemistry Research: Used as a core scaffold for constructing compound libraries in high-throughput screening (HTS) and structure-activity relationship (SAR) studies.
• Organic Synthesis Building Block: Employed in multi-step synthesis for introducing the complex pyrido[1,2-a]pyrimidine moiety into target molecules.
• Contract Research & Manufacturing (CRAM): Supplied to CDMOs and CROs for custom synthesis projects and process development for clinical trial materials.
• Academic Research: Utilized in university and institutional labs for investigating novel heterocyclic chemistry and reaction methodologies.

Basic Information

Product Name	Ethyl 6-Oxo-2,3,4,6-Tetrahydro-1H-Pyrido[1,2-A]Pyrimidine-9-Carboxylate
CAS No.	1020253-86-4
Molecular Formula	C12H14N2O3
Molecular Weight	234.25 g/mol
Synonyms	Ethyl 6-oxo-2,3,4,6-tetrahydro-1H-pyrido[1,2-a]pyrimidine-9-carboxylate; 9-Carbethoxy-1,2,3,4-tetrahydro-6H-pyrido[1,2-a]pyrimidin-6-one; 1,2,3,4-Tetrahydro-6H-pyrido[1,2-a]pyrimidin-6-one, 9-carboxylic acid ethyl ester; Ethyl 1,2,3,4-tetrahydro-6-oxopyrido[1,2-a]pyrimidine-9-carboxylate; 9-Ethoxycarbonyl-1,2,3,4-tetrahydro-6H-pyrido[1,2-a]pyrimidin-6-one
EINECS	Contact for details

Quality Control

Our Ethyl 6-Oxo-2,3,4,6-Tetrahydro-1H-Pyrido[1,2-A]Pyrimidine-9-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data are available upon request to support your quality and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.