Description

5-(Trifluoromethyl)Imidazo[1,2-A]Pyrimidine is a high-value, fluorinated heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in the unique electronic and steric properties imparted by the trifluoromethyl group, which is critical for modulating the biological activity and physicochemical characteristics of target molecules. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, particularly for central nervous system (CNS) and anti-infective therapies.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides, where the trifluoromethyl group enhances lipophilicity and metabolic stability.
• Material Science Research: Serves as a precursor for specialty chemicals and functional materials, such as organic semiconductors or ligands for catalysis.
• Chemical Biology & Proteomics: Employed as a molecular scaffold or tag in the design of chemical probes for studying biological systems and protein function.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scaled-up production under cGMP conditions for clinical trials.

Basic Information

Product Name	5-(Trifluoromethyl)Imidazo[1,2-A]Pyrimidine
CAS No.	1020033-87-7
Molecular Formula	C7H4F3N3
Molecular Weight	187.12 g/mol
Synonyms	5-(Trifluoromethyl)imidazo[1,2-a]pyrimidine; Imidazo[1,2-a]pyrimidine, 5-(trifluoromethyl)-; 5-Trifluoromethylimidazo[1,2-a]pyrimidine; 1020033-87-7; AI3-33255; ZINC00064410; SCHEMBL188284; CTK8G7225
EINECS	Contact for details

Quality Control

Every batch of 5-(Trifluoromethyl)Imidazo[1,2-A]Pyrimidine is manufactured and tested under a strict quality management system. We provide comprehensive analytical data including HPLC purity, NMR (1H, 19F, 13C), and mass spectrometry to ensure identity and quality. A detailed Certificate of Analysis (COA) is supplied with each shipment, confirming compliance with customer specifications and relevant industry standards for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.