Description

3,4-Difluoro-n-(4-Fluorobenzyl)Aniline, 97% is a high-purity fluorinated aniline derivative, serving as a critical building block in advanced organic synthesis. Its value lies in providing a versatile aromatic amine core with multiple fluorine substitution points, enabling precise tuning of electronic and steric properties in target molecules. This compound is essential for R&D chemists and process development scientists in the pharmaceutical and agrochemical industries, where it is used to create novel active ingredients with enhanced metabolic stability and bioavailability.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors, antiviral agents, and central nervous system (CNS) drugs.
• Agrochemical Synthesis: Building block for developing new herbicides, fungicides, and insecticides, where fluorine atoms improve lipophilicity and environmental stability.
• Material Science Research: Used in the creation of specialty polymers, liquid crystals, and organic electronic materials due to its fluorinated aromatic structure.
• Chemical Biology & Proteomics: Serves as a derivatization agent or a linker component in the design of chemical probes and affinity tags.
• Custom Synthesis & Contract Manufacturing: Supplied to CROs and CDMOs for client-directed synthesis projects requiring specific fluorinated aniline motifs.

Basic Information

Product Name	3,4-Difluoro-n-(4-Fluorobenzyl)Aniline, 97%
CAS No.	1019621-42-1
Molecular Formula	C13H10F3N
Molecular Weight	237.22 g/mol
Synonyms	N-[(4-Fluorophenyl)methyl]-3,4-difluoroaniline; 3,4-Difluoro-N-(4-fluorobenzyl)benzenamine; 1-[(4-Fluorophenyl)methyl]amino-3,4-difluorobenzene; Benzenamine, 3,4-difluoro-N-[(4-fluorophenyl)methyl]-; 4-Fluorobenzyl-(3,4-difluorophenyl)amine; N-(4-Fluorobenzyl)-3,4-difluoroaniline; 3,4-Difluoro-N-(4-fluorobenzyl)aniline
EINECS	Contact for details

Quality Control

Every batch of 3,4-Difluoro-n-(4-Fluorobenzyl)Aniline is produced and tested under a strict quality management system. We guarantee a minimum purity of 97% (by HPLC), with comprehensive impurity profiling to ensure consistency for sensitive synthetic applications. Certificates of Analysis (COA) detailing purity, identity, and specific tests are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents and acids. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.