Description

2,4-Difluoro-n-(Pyridin-2-Ylmethyl)Aniline is a high-purity, fluorinated aromatic amine derivative that serves as a critical building block in advanced organic synthesis. This compound is valued for its unique molecular scaffold, which combines a difluoroaniline moiety with a pyridinylmethyl group, enabling precise structural modifications. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, oncology, and anti-infective therapies.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, where the fluorine atoms and aniline core can enhance biological activity and environmental stability.
• Ligand Synthesis: Serves as a starting material for constructing complex ligands used in catalysis, such as for cross-coupling reactions or asymmetric synthesis.
• Material Science: Employed in the research and development of advanced organic electronic materials, including semiconductors and light-emitting diodes (OLEDs).
• Chemical Biology Probe Development: Utilized as a scaffold for creating molecular probes to study enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific custom synthesis projects.

Basic Information

Product Name	2,4-Difluoro-n-(Pyridin-2-Ylmethyl)Aniline
CAS No.	1019614-22-2
Molecular Formula	C₁₂H₁₀F₂N₂
Molecular Weight	220.22 g/mol
Synonyms	N-[(Pyridin-2-yl)methyl]-2,4-difluoroaniline; 2,4-Difluoro-N-(pyridin-2-ylmethyl)aniline; 2,4-Difluoro-N-(2-pyridylmethyl)aniline; 2,4-Difluoroaniline, N-(2-pyridinylmethyl)-; 1-(2,4-Difluorophenyl)-1-(pyridin-2-yl)methanamine; (2,4-Difluorophenyl)(pyridin-2-ylmethyl)amine; 1019614-22-2
EINECS	Contact for details

Quality Control

Every batch of 2,4-Difluoro-n-(Pyridin-2-Ylmethyl)Aniline is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the precise requirements for research and scale-up. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for each lot. Our standard quality commitment aligns with cGMP principles for advanced intermediates, ensuring traceability and consistency for critical development work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound may be light-sensitive and should be handled under an inert atmosphere for long-term storage to prevent degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.