Description

5-Fluoro-n-(4-Fluorobenzyl)-2-Methylaniline is a high-purity fluorinated aniline derivative, a critical building block in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of active pharmaceutical ingredients (APIs) and functional materials, where its specific fluorine substitution pattern enables precise tuning of biological activity and physicochemical properties. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel compounds with enhanced efficacy and stability.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Used in the development of new-generation herbicides and pesticides, where fluorine atoms improve metabolic stability and bioavailability.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorinated aromatic components in electronic display and lighting materials.
• Polymer Modification: Employed to introduce fluorine-containing aniline moieties into polymer backbones, enhancing material properties like chemical resistance and thermal stability.
• Chemical Biology Probes: Utilized in the design of fluorescent tags and molecular probes for diagnostic and research applications.
• Cross-Coupling Reactions: Acts as a substrate in palladium-catalyzed reactions (e.g., Buchwald-Hartwig amination) for constructing complex nitrogen-containing heterocycles.

Basic Information

Product Name	5-Fluoro-n-(4-Fluorobenzyl)-2-Methylaniline
CAS No.	1019514-90-9
Molecular Formula	C14H13F2N
Molecular Weight	233.26 g/mol
Synonyms	2-Methyl-5-fluoro-N-[(4-fluorophenyl)methyl]aniline; N-(4-Fluorobenzyl)-5-fluoro-2-methylaniline; 5-Fluoro-2-methyl-N-(4-fluorobenzyl)aniline; Benzenamine, 5-fluoro-N-[(4-fluorophenyl)methyl]-2-methyl-; 5-Fluoro-N-(4-fluorobenzyl)-2-methylbenzenamine
EINECS	Contact for details

Quality Control

Our 5-Fluoro-n-(4-Fluorobenzyl)-2-Methylaniline is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques including HPLC, GC, and NMR to confirm identity and assay. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.