Description

2-[(2,2-Difluoroethyl)Thio]Aniline is a specialized aromatic amine derivative featuring a difluoroethylthio substituent, serving as a high-value building block in advanced organic synthesis. Its molecular architecture, combining an aniline core with a fluorinated sulfur linker, makes it a critical intermediate for constructing complex molecules with tailored properties. This compound is primarily sought by research and development teams in the pharmaceutical and agrochemical sectors for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, particularly for central nervous system (CNS) and oncology targets.
• Agrochemical Synthesis: Building block for developing new-generation herbicides, fungicides, and insecticides with enhanced efficacy.
• Material Science Research: Used in the development of advanced polymers and liquid crystals where fluorine and sulfur incorporation modifies material properties.
• Organic Light-Emitting Diode (OLED) Materials: Intermediate for synthesizing electron-transport or host materials in display technologies.
• Ligand and Catalyst Development: Serves as a starting point for creating novel ligands in asymmetric catalysis and metal-organic frameworks (MOFs).
• Custom Synthesis and Contract Research: Supplied to CROs and CDMOs for client-specific research projects and scale-up activities.

Basic Information

Product Name	2-[(2,2-Difluoroethyl)Thio]Aniline
CAS No.	1018142-89-6
Molecular Formula	C8H9F2NS
Molecular Weight	189.23 g/mol
Synonyms	2-[(2,2-Difluoroethyl)sulfanyl]aniline; 2-[(2,2-Difluoroethyl)thio]benzenamine; 1-Amino-2-[(2,2-difluoroethyl)thio]benzene; Aniline, 2-[(2,2-difluoroethyl)thio]-; 2-(2,2-Difluoroethylthio)aniline; Benzenamine, 2-[(2,2-difluoroethyl)thio]-; 1018142-89-6
EINECS	Contact for details

Quality Control

Our 2-[(2,2-Difluoroethyl)Thio]Aniline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, GC for residual solvents, and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and scale-up. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents. For long-term storage, consider an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	Light yellow to brown liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.