Description

3-[5-Methyl-7-(Trifluoromethyl)[1,2,4]Triazolo[1,5-A]Pyrimidin-2-Yl]Propanoic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its unique triazolopyrimidine core and trifluoromethyl group. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring specific molecular scaffolds. It is primarily sought by research institutions and manufacturers in the pharmaceutical and agrochemical industries for the development of new drug candidates and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders, inflammatory diseases, and oncology.
• Agrochemical Research: Serves as a building block for developing new generation pesticides and herbicides, leveraging the biological activity of the triazolopyrimidine structure.
• Chemical Synthesis: Used in organic synthesis for constructing complex heterocyclic compounds in medicinal and process chemistry.
• Bioconjugation & Probe Development: The carboxylic acid functional group allows for conjugation to other molecules, making it useful in creating biochemical probes and labeled compounds for research.

Basic Information

Product Name	3-[5-Methyl-7-(Trifluoromethyl)[1,2,4]Triazolo[1,5-A]Pyrimidin-2-Yl]Propanoic Acid
CAS No.	1018052-06-6
Molecular Formula	C11H9F3N4O2
Molecular Weight	286.21 g/mol
Synonyms	3-(5-Methyl-7-(trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl)propanoic acid; 2-[3-(5-Methyl-7-trifluoromethyl-[1,2,4]triazolo[1,5-a]pyrimidinyl)]propionic Acid; 1018052-06-6; 3-(5-Methyl-7-(trifluoromethyl)-1,2,4-triazolo[1,5-a]pyrimidin-2-yl)propanoic acid; Propanoic acid, 3-[5-methyl-7-(trifluoromethyl)[1,2,4]triazolo[1,5-a]pyrimidin-2-yl]-
EINECS	Contact for details

Quality Control

Our 3-[5-Methyl-7-(Trifluoromethyl)[1,2,4]Triazolo[1,5-A]Pyrimidin-2-Yl]Propanoic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting all critical quality attributes. Our production adheres to cGMP guidelines where applicable, ensuring reliability for your most demanding research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to prevent degradation. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.