Description

3-[5-(3-Methyl-5-Isoxazolyl)-2-(Methylsulfonyl)-4-Pyrimidinyl]-1-Piperidinecarboxylic Acid,1,1-Dimethylethyl Ester is a sophisticated heterocyclic building block and advanced pharmaceutical intermediate of significant interest in modern drug discovery. This compound is valued for its unique molecular architecture, which combines isoxazole, pyrimidine, and piperidine motifs, enabling the synthesis of novel bioactive molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, particularly in areas requiring complex small-molecule scaffolds.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel active pharmaceutical ingredients (APIs) for preclinical and clinical research.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Chemical Biology Probes: Employed in the development of chemical probes to study biological pathways and protein functions.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis services catering to the pharmaceutical and biotechnology industries.
• Library Synthesis: Utilized in the generation of diverse compound libraries for high-throughput screening against various biological targets.

Basic Information

Product Name	3-[5-(3-Methyl-5-Isoxazolyl)-2-(Methylsulfonyl)-4-Pyrimidinyl]-1-Piperidinecarboxylic Acid,1,1-Dimethylethyl Ester
CAS No.	1017793-03-1
Molecular Formula	C20H26N4O5S
Molecular Weight	434.51 g/mol
Synonyms	tert-Butyl 3-[5-(3-methyl-1,2-oxazol-5-yl)-2-(methylsulfonyl)pyrimidin-4-yl]piperidine-1-carboxylate; 1-Piperidinecarboxylic acid, 3-[5-(3-methyl-5-isoxazolyl)-2-(methylsulfonyl)-4-pyrimidinyl]-, 1,1-dimethylethyl ester; 1-(tert-Butoxycarbonyl)-3-[5-(3-methylisoxazol-5-yl)-2-(methylsulfonyl)pyrimidin-4-yl]piperidine; CAS 1017793-03-1
EINECS	Contact for details

Quality Control

Our production of 3-[5-(3-Methyl-5-Isoxazolyl)-2-(Methylsulfonyl)-4-Pyrimidinyl]-1-Piperidinecarboxylic Acid,1,1-Dimethylethyl Ester adheres to stringent quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the exacting standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity (typically ≥95% by HPLC), identity confirmation (by NMR and MS), and impurity profile is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). For long-term storage, consider storing under an inert atmosphere to maintain stability. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.