Description

2-Ethoxy-3,5-Difluoroaniline is a specialized aromatic amine derivative, distinguished by its ethoxy and difluoro substituents, which impart unique reactivity and electronic properties. This compound serves as a critical high-purity intermediate in advanced organic synthesis, where its structural motifs are essential for constructing complex molecular architectures. It is primarily utilized by research and development teams in the pharmaceutical and agrochemical sectors for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring a difluorinated aniline core.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, where the fluorine atoms enhance biological activity and stability.
• Material Science Research: Employed in the development of specialty polymers, liquid crystals, and organic electronic materials due to its modified aromatic structure.
• Dye and Pigment Intermediate: Serves as a precursor in the manufacture of specialized dyes and pigments where fluorine substitution alters color and lightfastness properties.
• Cross-Coupling Reactions: Acts as a valuable substrate in palladium-catalyzed reactions, such as Buchwald-Hartwig amination, for creating complex nitrogen-containing compounds.

Basic Information

Product Name	2-Ethoxy-3,5-Difluoroaniline
CAS No.	1017779-76-8
Molecular Formula	C8H9F2NO
Molecular Weight	173.16 g/mol
Synonyms	3,5-Difluoro-2-ethoxyaniline; 2-Amino-1,3-difluoro-5-ethoxybenzene; Benzenamine, 3,5-difluoro-2-ethoxy-; 2-Ethoxy-3,5-difluorobenzenamine; 3,5-Difluoro-2-ethoxybenzenamine; 2-Ethoxy-3,5-difluoro-phenylamine
EINECS	Contact for details

Quality Control

Every batch of 2-Ethoxy-3,5-Difluoroaniline is manufactured under a cGMP-compliant quality management system and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our products are supported by comprehensive Certificates of Analysis (COA), detailing results from HPLC, GC, NMR, and other relevant tests. We are committed to meeting the stringent requirements of pharmaceutical and research-grade applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flames. Due to its light-sensitive nature, containers should be amber-colored or stored in light-resistant packaging.

Specification

Item	Specification
Appearance	Light yellow to brown crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.