Description

4-Ethoxy-3,5-Difluorobenzylbromide is a high-value fluorinated benzyl bromide derivative, a crucial building block in advanced organic synthesis. Its molecular structure, featuring both ethoxy and difluoro substituents, makes it an essential intermediate for creating complex molecules with tailored electronic and steric properties. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and fungicides, where the difluoro and ethoxy groups contribute to enhanced biological activity and environmental stability.
• Liquid Crystal Materials: Serves as a precursor in the production of fluorinated liquid crystals for advanced display technologies (LCDs).
• Organic Electronics: Employed in the synthesis of conjugated polymers and small molecules for organic light-emitting diodes (OLEDs) and organic photovoltaics (OPVs).
• Cross-Coupling Reactions: Acts as an efficient electrophile in Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form biaryl structures.
• Chemical Research & Development: A versatile reagent in academic and industrial R&D for exploring new synthetic methodologies and creating compound libraries for screening.

Basic Information

Product Name	4-Ethoxy-3,5-Difluorobenzylbromide
CAS No.	1017779-38-2
Molecular Formula	C9H9BrF2O
Molecular Weight	251.07 g/mol
Synonyms	1-(Bromomethyl)-4-ethoxy-3,5-difluorobenzene; 3,5-Difluoro-4-ethoxybenzyl Bromide; (4-ethoxy-3,5-difluorophenyl)methyl bromide; 4-Ethoxy-3,5-difluorobenzyl bromide; 4-Ethoxy-3,5-difluorobenzyl bromide (CAS 1017779-38-2); 4-Ethoxy-3,5-difluorobenzylbromide; 4-Ethoxy-3,5-difluorobenzyl bromide, 97+%
EINECS	Contact for details

Quality Control

Our 4-Ethoxy-3,5-Difluorobenzylbromide is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for demanding synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing key parameters such as purity (by HPLC/NMR), identity confirmation, and impurity profiles. Our quality management system is designed to meet the rigorous standards required for pharmaceutical and advanced material research.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This compound is light-sensitive (store away from light) and should be handled with appropriate precautions for strong acids/organic solvents. Keep away from heat, sparks, and open flames.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.