Description

2-Methoxy-3-(Trifluoromethyl)Benzyl Alcohol is a versatile fluorinated aromatic building block of significant interest in advanced organic synthesis. Its value lies in the unique combination of the methoxy and trifluoromethyl substituents, which can dramatically influence the lipophilicity, metabolic stability, and binding affinity of target molecules. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials and organic light-emitting diodes (OLEDs), improving charge transport and stability.
• Advanced Polymer Chemistry: Incorporated into specialty polymers to impart specific properties such as chemical resistance, low surface energy, or modified refractive index.
• Chemical Research & Development: Employed in academic and industrial R&D for methodology development, catalysis studies, and the exploration of new chemical spaces in medicinal chemistry.

Basic Information

Product Name	2-Methoxy-3-(Trifluoromethyl)Benzyl Alcohol
CAS No.	1017778-74-3
Molecular Formula	C10H11F3O2
Molecular Weight	220.19 g/mol
Synonyms	[2-Methoxy-3-(trifluoromethyl)phenyl]methanol; 1-(2-Methoxy-3-(trifluoromethyl)phenyl)methanol; 2-Methoxy-α-(trifluoromethyl)benzenemethanol; 3-(Trifluoromethyl)-2-methoxybenzyl alcohol; (2-Methoxy-3-(trifluoromethyl)phenyl)methanol; Benzenemethanol, 2-methoxy-α-(trifluoromethyl)-; α-(Trifluoromethyl)-2-methoxybenzenemethanol
EINECS	Contact for details

Quality Control

Our 2-Methoxy-3-(Trifluoromethyl)Benzyl Alcohol is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing specifications such as assay (by HPLC), identity confirmation (IR, NMR), and impurity profiles. Our quality commitment supports compliance with cGMP and ISO standards for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and oxidizing agents. Due to its sensitivity, the container should be kept tightly sealed when not in use to minimize exposure to moisture and air.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.