Description

2-Fluoro-4,6-Bis(trifluoromethyl)benzyl alcohol is a high-value fluorinated aromatic building block characterized by its unique trifluoromethyl and benzyl alcohol functional groups. This compound is critical for introducing lipophilicity, metabolic stability, and electronic effects into advanced molecular architectures. It is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, including potential drug candidates and crop protection agents.

Application

• Pharmaceutical Intermediate: A key synthon for the development of fluorinated active pharmaceutical ingredients (APIs), particularly in oncology, CNS, and antiviral research.
• Agrochemical Synthesis: Used in creating advanced herbicides, fungicides, and insecticides where the fluorine atoms enhance biological activity and environmental stability.
• Liquid Crystal Materials: Serves as a precursor for fluorinated components in liquid crystal displays (LCDs), improving dielectric anisotropy and thermal stability.
• Organic Electronics: Employed in the synthesis of materials for organic light-emitting diodes (OLEDs) and semiconductors due to its electron-withdrawing properties.
• Advanced Polymer Chemistry: Acts as a monomer or modifier to incorporate fluorine into high-performance polymers, enhancing chemical resistance and surface properties.
• Chemical Research & Development: A versatile building block in medicinal chemistry and material science for structure-activity relationship (SAR) studies and novel compound libraries.

Basic Information

Product Name	2-Fluoro-4,6-Bis(trifluoromethyl)benzyl Alcohol
CAS No.	1017778-42-5
Molecular Formula	C10H5F7O
Molecular Weight	274.14 g/mol
Synonyms	2-Fluoro-α,α-bis(trifluoromethyl)-1-benzyl alcohol; (2-Fluoro-4,6-bis(trifluoromethyl)phenyl)methanol; 1-(2-Fluoro-4,6-bis(trifluoromethyl)phenyl)methanol; 2-Fluoro-4,6-bis(trifluoromethyl)benzenemethanol; α,α-Bis(trifluoromethyl)-2-fluorobenzyl alcohol
EINECS	Contact for details

Quality Control

Every batch of 2-Fluoro-4,6-Bis(trifluoromethyl)benzyl alcohol is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the precise requirements for advanced synthetic applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment, supporting compliance in regulated research and development environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.