Description

1-(3-Fluorophenyl)-2-Oxopyrrolidine-3-Carboxylic Acid is a high-purity fluorinated pyrrolidone derivative, serving as a critical building block in advanced organic synthesis. This compound matters for its role in constructing complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs). Pharmaceutical researchers and fine chemical manufacturers need it for its unique structural features that enable the creation of targeted therapeutic agents with potential neurological and metabolic applications.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and anti-inflammatory targets.
• Active Pharmaceutical Ingredient (API) Synthesis: Used in the multi-step synthesis of complex APIs, leveraging the fluorophenyl and pyrrolidone motifs for bioactivity.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies to optimize the pharmacokinetic and pharmacodynamic properties of lead compounds.
• Chemical Biology Probes: Serves as a scaffold for developing molecular probes to study enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-purity fluorinated intermediates.
• Academic & Industrial R&D: Utilized in research laboratories for exploring new synthetic methodologies and heterocyclic chemistry.

Basic Information

Product Name	1-(3-Fluorophenyl)-2-Oxopyrrolidine-3-Carboxylic Acid
CAS No.	1017473-77-6
Molecular Formula	C11H10FNO3
Molecular Weight	223.20 g/mol
Synonyms	3-Carboxy-1-(3-fluorophenyl)-2-pyrrolidinone; 1-(3-Fluorophenyl)-3-carboxy-2-pyrrolidinone; 2-Oxo-1-(3-fluorophenyl)pyrrolidine-3-carboxylic acid; 3-Pyrrolidinecarboxylic acid, 1-(3-fluorophenyl)-2-oxo-; 1-(3-Fluorophenyl)-2-oxopyrrolidine-3-carboxylic acid; 1-(3-Fluorophenyl)-2-pyrrolidinone-3-carboxylic acid; 3-Carboxy-1-(m-fluorophenyl)-2-pyrrolidinone
EINECS	Contact for details

Quality Control

Our 1-(3-Fluorophenyl)-2-Oxopyrrolidine-3-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring the material meets the stringent requirements for pharmaceutical R&D and scale-up.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.