Description

4-Methyl-2-(trifluoromethyl)pyrimidine is a high-value fluorinated pyrimidine building block essential for advanced organic synthesis. Its unique structure, featuring both a methyl and a trifluoromethyl group on the pyrimidine ring, makes it a critical intermediate for introducing lipophilicity and metabolic stability into target molecules. This compound is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of kinase inhibitors, antiviral agents, and other small-molecule therapeutics.
• Agrochemical Research: Used in the discovery and synthesis of new herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Material Science Precursor: Serves as a monomer or functionalizing agent in the development of advanced polymers, liquid crystals, and electronic materials.
• Chemical Synthesis Reagent: Employed in cross-coupling reactions, nucleophilic substitutions, and as a scaffold for constructing complex heterocyclic compounds in medicinal chemistry.

Basic Information

Product Name	4-Methyl-2-(trifluoromethyl)pyrimidine
CAS No.	1017464-05-9
Molecular Formula	C6H5F3N2
Molecular Weight	162.11 g/mol
Synonyms	2-(Trifluoromethyl)-4-methylpyrimidine; 4-Methyl-2-(trifluoromethyl)pyrimidine; 4-Methyl-2-trifluoromethylpyrimidine; Pyrimidine, 4-methyl-2-(trifluoromethyl)-; 1017464-05-9
EINECS	Contact for details

Quality Control

Our 4-Methyl-2-(trifluoromethyl)pyrimidine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research and scale-up applications. We provide comprehensive analytical data including HPLC purity, NMR, and MS confirmation. Certificates of Analysis (COA) detailing all specifications are available for every batch upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.