Description

1-(2-Fluorophenyl)Cyclobutanamine is a specialized fluorinated amine building block of significant interest in advanced organic synthesis. This compound matters for its role as a key precursor in the development of novel active pharmaceutical ingredients (APIs) and other high-value fine chemicals. Pharmaceutical research and development (R&D) laboratories, agrochemical innovators, and specialty chemical manufacturers are the primary industries that need this high-purity intermediate.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and psychiatric disorder research.
• Agrochemical Research: Used in the development of new pesticides and herbicides, where the fluorophenyl moiety can enhance biological activity and metabolic stability.
• Ligand Synthesis: Acts as a precursor for creating specialized ligands used in catalysis and material science applications.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis projects and scale-up production under cGMP conditions for clinical trials.

Basic Information

Product Name	1-(2-Fluorophenyl)Cyclobutanamine
CAS No.	1017391-62-6
Molecular Formula	C10H12FN
Molecular Weight	165.21 g/mol
Synonyms	1-(2-Fluorophenyl)cyclobutanamine; 2-Fluoro-α-cyclobutylbenzenemethanamine; 1-(2-Fluorophenyl)cyclobutan-1-amine; Cyclobutanamine, 1-(2-fluorophenyl)-; 1017391-62-6; 1-(2-Fluorophenyl)cyclobutylamine; 2-Fluorophenyl cyclobutyl amine
EINECS	Contact for details

Quality Control

Our 1-(2-Fluorophenyl)Cyclobutanamine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and moisture. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.