Description

4-Hydroxy-2-(Trifluoromethoxy)Benzaldehyde is a specialized aromatic aldehyde featuring both a phenolic hydroxyl group and a trifluoromethoxy substituent. This unique molecular structure makes it a valuable and versatile building block for advanced organic synthesis, particularly in the development of novel active compounds. It is primarily sought after by R&D and production teams in the pharmaceutical and agrochemical industries for creating new molecules with enhanced properties.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), especially for candidates targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Used to construct advanced herbicide and pesticide molecules, where the trifluoromethoxy group can improve lipophilicity, metabolic stability, and biological activity.
• Liquid Crystal & OLED Material Research: Serves as a starting material for synthesizing fluorinated aromatic cores used in electronic display technologies and organic light-emitting diodes.
• Functional Polymer Monomer: Incorporated into polymer backbones to impart specific characteristics like chemical resistance, thermal stability, or unique optical properties.
• Complex Ligand & Catalyst Development: Utilized in organometallic chemistry to create sophisticated chelating ligands for catalysis and material science applications.
• Advanced Dye & Pigment Chemistry: Acts as an intermediate for producing specialized fluorinated dyes with potential applications in imaging and sensing.

Basic Information

Product Name	4-Hydroxy-2-(Trifluoromethoxy)Benzaldehyde
CAS No.	1017083-37-2
Molecular Formula	C8H5F3O3
Molecular Weight	206.12 g/mol
Synonyms	2-(Trifluoromethoxy)-4-hydroxybenzaldehyde; 4-Hydroxy-2-(trifluoromethoxy)benzaldehyde; 4-Hydroxy-2-trifluoromethoxybenzaldehyde; 2-Trifluoromethoxy-4-hydroxybenzaldehyde; 4-Hydroxy-α,α,α-trifluoro-o-anisaldehyde; Salicylaldehyde, 2-(trifluoromethoxy)-; Benzaldehyde, 4-hydroxy-2-(trifluoromethoxy)-
EINECS	Contact for details

Quality Control

We maintain strict quality control protocols for all our fine chemical intermediates. Production of 4-Hydroxy-2-(Trifluoromethoxy)Benzaldehyde follows current Good Manufacturing Practices (cGMP) where applicable, and each batch is analyzed to ensure it meets stringent purity specifications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended storage temperature is 2-8°C for long-term stability. This compound is easily oxidized and moisture-sensitive; ensure containers are sealed immediately after use to minimize exposure to air and humidity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.