Description

3,3,3-Trifluoro-1-(4-Fluorophenyl)Propan-1-Amine is a high-value fluorinated aromatic amine building block, essential for introducing unique physicochemical properties into advanced molecular architectures. Its core value lies in enabling the synthesis of complex, biologically active compounds with enhanced metabolic stability and membrane permeability. This intermediate is critically needed by pharmaceutical and agrochemical R&D teams for the development of new active ingredients, particularly in the areas of medicinal chemistry and crop protection.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel active pharmaceutical ingredients (APIs), especially for central nervous system (CNS) and oncology targets.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides where the trifluoromethyl and fluorophenyl groups confer desirable activity and environmental fate.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Incorporated into specialty polymers and advanced organic materials to modify thermal stability, solubility, and electronic properties.
• Fluorine Chemistry Research: A valuable compound for academic and industrial research exploring new fluorination methodologies and the effects of fluorine substitution.
• Diagnostic Agent Precursor: Potential use in the synthesis of radiolabeled compounds or contrast agents for medical imaging.

Basic Information

Product Name	3,3,3-Trifluoro-1-(4-Fluorophenyl)Propan-1-Amine
CAS No.	1016742-86-1
Molecular Formula	C9H7F4N
Molecular Weight	205.15 g/mol
Synonyms	1-(4-Fluorophenyl)-3,3,3-trifluoropropan-1-amine; 3,3,3-Trifluoro-1-(4-fluorophenyl)-1-propanamine; 4-Fluoro-α-(trifluoromethyl)benzylamine; γ,γ,γ-Trifluoro-4-fluorophenethylamine; 4-Fluoro-α-(trifluoromethyl)benzenemethanamine; (4-Fluorophenyl)(3,3,3-trifluoropropyl)amine; 1016742-86-1
EINECS	Contact for details

Quality Control

Every batch of 3,3,3-Trifluoro-1-(4-Fluorophenyl)Propan-1-Amine is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the exacting standards required for research and scale-up activities. A detailed Certificate of Analysis (COA) confirming identity, purity, and impurity profiles via techniques such as HPLC, GC, NMR, and IR spectroscopy is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Standard Grade)
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 1.0%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.