Description

1-(4-Fluorophenyl)-2,2-Dimethylpropan-1-Amine is a specialized organic building block featuring a fluorinated aromatic ring and a sterically hindered amine group. This unique molecular architecture makes it a valuable intermediate for the synthesis of advanced pharmaceuticals and agrochemicals, where the fluorine atom and the amine functionality are critical for modulating biological activity and physicochemical properties. It is primarily sought by research and development chemists in the pharmaceutical, agrochemical, and fine chemical industries for creating novel active ingredients and complex molecules. The compound is supplied under stringent quality control to ensure consistency for sensitive synthetic applications.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) agents, anti-inflammatory drugs, and other bioactive molecules.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the fluorine moiety enhances lipophilicity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands or organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed as a monomer or functionalizing agent in the development of specialty polymers and advanced organic materials.
• Chemical Biology & Proteomics: Utilized as a building block for creating molecular probes and activity-based protein profiling (ABPP) reagents.
• Academic & Contract Research: A valuable reagent for methodological studies and discovery chemistry in university and CRO laboratories.

Basic Information

Item	Details
Product Name	1-(4-Fluorophenyl)-2,2-Dimethylpropan-1-Amine
CAS No.	1016506-81-2
Molecular Formula	C11H16FN
Molecular Weight	181.25 g/mol
Synonyms	1-(4-Fluorophenyl)-2,2-dimethylpropan-1-amine; 4-Fluoro-α,α-dimethylbenzenemethanamine; p-Fluoro-α,α-dimethylbenzylamine; 1-Amino-2,2-dimethyl-1-(4-fluorophenyl)propane; (4-Fluorophenyl)(1,1-dimethylethyl)methanamine; 2,2-Dimethyl-1-(4-fluorophenyl)propan-1-amine; 4-Fluoro-α,α-dimethylbenzylamine; Tert-butyl(4-fluorophenyl)methylamine
EINECS	Contact for details

Quality Control

Our 1-(4-Fluorophenyl)-2,2-Dimethylpropan-1-Amine is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring traceability and reliability for our global B2B clients in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and performance. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.