Description

4-Fluoro-7H-Pyrrolo[2,3-D]Pyrimidine-6-Carboxylic Acid is a high-purity, fluorinated heterocyclic building block of significant interest in advanced organic synthesis. This compound matters because it serves as a critical scaffold for constructing novel molecules with targeted biological activity, particularly in the pharmaceutical sector. It is primarily needed by research chemists and process development scientists in pharmaceutical, agrochemical, and biotechnology industries for drug discovery and development programs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of kinase inhibitors and other small-molecule therapeutics targeting various disease pathways.
• Agrochemical Research: Used in the development of new active ingredients for crop protection, leveraging its unique fluorinated pyrrolopyrimidine core.
• Chemical Biology Probe Development: Employed as a core structure for creating tool compounds to study enzyme function and cellular signaling processes.
• Material Science: Potential building block for advanced organic electronic materials due to its conjugated heterocyclic system.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting outsourced drug discovery and custom synthesis projects.
• Academic Research: Utilized in university and institutional labs for methodological studies in fluorination chemistry and heterocycle synthesis.

Basic Information

Product Name	4-Fluoro-7H-Pyrrolo[2,3-D]Pyrimidine-6-Carboxylic Acid
CAS No.	1016241-81-8
Molecular Formula	C7H4FN3O2
Molecular Weight	181.13 g/mol
Synonyms	4-Fluoro-7H-pyrrolo[2,3-d]pyrimidine-6-carboxylic acid; 6-Carboxy-4-fluoro-7H-pyrrolo[2,3-d]pyrimidine; 4-Fluoro-1H-pyrrolo[2,3-d]pyrimidine-6-carboxylic acid; 4-Fluoro-7H-pyrrolo[2,3-d]pyrimidine-6-carboxylic acid (CAS 1016241-81-8); 4-Fluoro-7H-pyrrolo[2,3-d]pyrimidine-6-carboxylate; 4-Fluoro-1H-pyrrolo[2,3-d]pyrimidine-6-carboxylate; 4-Fluoro-7H-pyrrolo[2,3-d]pyrimidine-6-carboxylic acid, 1016241-81-8
EINECS	Contact for details

Quality Control

Our 4-Fluoro-7H-Pyrrolo[2,3-D]Pyrimidine-6-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure compliance with exacting standards for research and development use. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere if necessary to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.