Description

1-(5-Bromopyrimidin-2-yl)azepane is a high-purity, functionalized heterocyclic building block of significant interest in advanced organic synthesis. This compound is valued for its unique molecular architecture, which combines a brominated pyrimidine core with a seven-membered azepane ring, offering versatile reactivity for constructing complex pharmacophores. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the discovery and development of new active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel small molecule drug candidates, particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic scaffold for bioactivity.
• Chemical Biology Probe: Employed in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Material Science Building Block: Acts as a monomer or functional unit in the creation of specialty polymers and advanced organic materials.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up processes under cGMP or ISO standards.

Basic Information

Product Name	1-(5-Bromopyrimidin-2-yl)azepane
CAS No.	1015241-96-9
Molecular Formula	C10H14BrN3
Molecular Weight	256.14 g/mol
Synonyms	Azepane, 1-(5-bromo-2-pyrimidinyl)-; 1-(5-Bromopyrimidin-2-yl)azepane; 5-Bromo-2-(azepan-1-yl)pyrimidine; 2-(1-Azepanyl)-5-bromopyrimidine; 5-Bromo-2-(hexamethyleneimino)pyrimidine; 1015241-96-9
EINECS	Contact for details

Quality Control

Our 1-(5-Bromopyrimidin-2-yl)azepane is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes. We support development and commercial projects requiring compliance with various pharmacopeial or internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled and stored away from direct light. Keep the container tightly sealed when not in use to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.