Description

1-(2-Pyrimidinyl)-1H-Pyrazole-4-Carboxylic Acid CAS NO 1014632-18-8 is a high-purity heterocyclic building block featuring a pyrazole core fused with a pyrimidine ring. This compound is valued for its role as a critical intermediate in the synthesis of complex pharmaceutical molecules and advanced agrochemicals. It is primarily sought by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for developing new active ingredients.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly in kinase inhibitor research.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides.
• Chemical Research: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies.
• Material Science: Potential precursor for the development of organic electronic materials and metal-organic frameworks (MOFs).
• Bioconjugation: The carboxylic acid group allows for coupling reactions to create labeled probes or targeted biomolecules.

Basic Information

Product Name	1-(2-Pyrimidinyl)-1H-Pyrazole-4-Carboxylic Acid
CAS No.	1014632-18-8
Molecular Formula	C8H6N4O2
Molecular Weight	190.16 g/mol
Synonyms	1-(Pyrimidin-2-yl)-1H-pyrazole-4-carboxylic acid; 1H-Pyrazole-4-carboxylic acid, 1-(2-pyrimidinyl)-; 1-(2-Pyrimidinyl)-1H-pyrazole-4-carboxylic acid; Pyrazole-4-carboxylic acid, 1-(2-pyrimidinyl)-; 1014632-18-8; 1-(Pyrimidin-2-yl)-1H-pyrazole-4-carboxylic acid; 1-(2-Pyrimidyl)-1H-pyrazole-4-carboxylic acid
EINECS	Contact for details

Quality Control

Our 1-(2-Pyrimidinyl)-1H-Pyrazole-4-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents, strong bases, and strong acids.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.