Description

4-Bromo-3-(Trifluoromethoxy)Benzyl Alcohol is a high-purity, multi-functional aromatic building block of significant interest in advanced organic synthesis. Its core value lies in the strategic combination of a reactive benzyl alcohol group with bromine and trifluoromethoxy substituents, enabling precise molecular construction. This compound is essential for research chemists and process development scientists in the pharmaceutical and agrochemical industries who require reliable, high-quality intermediates for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the trifluoromethoxy group can enhance biological activity and metabolic stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for synthesizing fluorinated aromatic cores used in electronic display technologies and organic light-emitting diodes (OLEDs).
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck, Sonogashira) to form complex biaryl structures.
• Functional Polymer Monomer: Can be incorporated into polymer backbones to impart specific properties like hydrophobicity, chemical resistance, or altered refractive index.
• Chemical Research & Development: A versatile building block for exploring new synthetic methodologies and creating custom chemical libraries for high-throughput screening.

Basic Information

Product Name	4-Bromo-3-(Trifluoromethoxy)Benzyl Alcohol
CAS No.	1011531-67-1
Molecular Formula	C8H6BrF3O2
Molecular Weight	271.04 g/mol
Synonyms	[4-Bromo-3-(trifluoromethoxy)phenyl]methanol; (4-Bromo-3-trifluoromethoxyphenyl)methanol; 1-Bromo-2-(hydroxymethyl)-4-(trifluoromethoxy)benzene; 4-Bromo-α-(trifluoromethoxy)benzenemethanol; 4-Bromo-3-(trifluoromethoxy)benzenemethanol; Benzyl alcohol, 4-bromo-3-(trifluoromethoxy)-
EINECS	Contact for details

Quality Control

Every batch of 4-Bromo-3-(Trifluoromethoxy)Benzyl Alcohol is manufactured and tested under a strict quality management system. Our products undergo rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency meet the exacting standards required for research and scale-up. Certificates of Analysis (COA) detailing all specifications are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Melting Point	Contact for details
Water Content (KF)	≤ 0.5% w/w
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.