Description

Ethyl 2-tert-Butyl-4-Chloropyrimidine-5-Carboxylate is a high-purity pyrimidine derivative serving as a critical building block in advanced organic synthesis. Its value lies in its functionalized structure, which provides a versatile scaffold for constructing complex molecules in pharmaceutical and agrochemical research. This compound is essential for medicinal chemists and process development scientists working on active pharmaceutical ingredients (APIs), crop protection agents, and other fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, particularly in kinase inhibitor and antiviral agent synthesis.
• Agrochemical Synthesis: Used as a precursor in the manufacture of advanced herbicides, fungicides, and insecticides.
• Chemical Research & Development: Serves as a versatile building block for constructing complex heterocyclic compounds in academic and industrial R&D labs.
• Material Science: Potential application as a monomer or precursor in the synthesis of specialty polymers and functional materials.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-purity intermediates.

Basic Information

Product Name	Ethyl 2-tert-Butyl-4-Chloropyrimidine-5-Carboxylate
CAS No.	1011464-42-8
Molecular Formula	C11H15ClN2O2
Molecular Weight	242.70 g/mol
Synonyms	2-tert-Butyl-4-chloro-5-pyrimidinecarboxylic acid ethyl ester; Ethyl 2-(tert-butyl)-4-chloropyrimidine-5-carboxylate; 4-Chloro-2-tert-butylpyrimidine-5-carboxylic acid ethyl ester; 1011464-42-8; 2-(1,1-Dimethylethyl)-4-chloro-5-pyrimidinecarboxylic acid ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 2-tert-Butyl-4-Chloropyrimidine-5-Carboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with every shipment, confirming compliance with customer specifications and internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents, strong acids, and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.