Description

2-{4-[(4-Bromophenyl)Carbonyl]Piperazin-1-Yl}-3-Methyl-5,6,7,8-Tetrahydro[1]Benzothieno[2,3-D]Pyrimidin-4(3H)-One is a high-purity, advanced pharmaceutical intermediate designed for research and development applications. This compound is valued for its complex heterocyclic structure, which serves as a critical building block in the synthesis of novel therapeutic agents. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing new drug candidates, particularly in oncology and central nervous system (CNS) research.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel small-molecule drug candidates targeting specific biological pathways.
• Kinase Inhibitor Research: Used in the development and screening of potential kinase inhibitors due to its benzothienopyrimidine core structure.
• Medicinal Chemistry R&D: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Biochemical Tool Compound: Employed in biochemical assays to study enzyme function and cellular signaling mechanisms.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for clinical trial materials.
• Academic Research: Used in university and institutional laboratories for fundamental research in organic chemistry and pharmacology.

Basic Information

Product Name	2-{4-[(4-Bromophenyl)Carbonyl]Piperazin-1-Yl}-3-Methyl-5,6,7,8-Tetrahydro[1]Benzothieno[2,3-D]Pyrimidin-4(3H)-One
CAS No.	1010927-48-6
Molecular Formula	C23H23BrN4O2S
Molecular Weight	499.42 g/mol
Synonyms	2-[4-(4-Bromobenzoyl)piperazin-1-yl]-3-methyl-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidin-4-one; 2-(4-(4-Bromobenzoyl)piperazin-1-yl)-3-methyl-5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidin-4(3H)-one; 1010927-48-6; UNII-9F8J3U7V3I; 9F8J3U7V3I; Benzothieno[2,3-d]pyrimidin-4(3H)-one, 2-[4-[(4-bromophenyl)carbonyl]-1-piperazinyl]-3-methyl-5,6,7,8-tetrahydro-
EINECS	Contact for details

Quality Control

Our 2-{4-[(4-Bromophenyl)Carbonyl]Piperazin-1-Yl}-3-Methyl-5,6,7,8-Tetrahydro[1]Benzothieno[2,3-D]Pyrimidin-4(3H)-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. Keep the container sealed to protect this light-sensitive material from moisture and atmospheric contaminants.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Retention time corresponds to reference standard
Identification (NMR)	Spectrum consistent with structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.