Description

(S)-4-(2-Chloro-6-(Iodomethyl)Pyrimidin-4-Yl)-3-Methylmorpholine is a high-purity, advanced pharmaceutical intermediate featuring a chiral morpholine scaffold. This compound is of significant value for its role in the synthesis of complex, biologically active molecules, particularly in medicinal chemistry. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, especially those targeting specific enzymatic pathways where stereochemistry is critical.

Application

• Pharmaceutical Intermediate: A key chiral building block in the research and development of novel active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for drug discovery programs.
• Synthesis of Kinase Inhibitors: Serves as a precursor in the synthesis of targeted small-molecule inhibitors, particularly for oncology applications.
• Asymmetric Synthesis: Utilized in the construction of complex molecules where the (S)-configured morpholine moiety is essential for biological activity.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up and cGMP production.
• Chemical Reference Standard: Serves as a high-purity analytical standard for quality control and method development.

Basic Information

Product Name	(S)-4-(2-Chloro-6-(Iodomethyl)Pyrimidin-4-Yl)-3-Methylmorpholine
CAS No.	1009628-22-1
Molecular Formula	C10H13ClIN3O
Molecular Weight	353.59 g/mol
Synonyms	(S)-3-Methyl-4-[2-chloro-6-(iodomethyl)pyrimidin-4-yl]morpholine; 4-(2-Chloro-6-(iodomethyl)-4-pyrimidinyl)-3-methylmorpholine, (S)-; (S)-4-(2-Chloro-6-(iodomethyl)pyrimidin-4-yl)-3-methylmorpholine; (S)-4-(2-Chloro-6-(iodomethyl)-4-pyrimidinyl)-3-methylmorpholine; (S)-4-(2-Chloro-6-(iodomethyl)pyrimidin-4-yl)-3-methylmorpholine CAS 1009628-22-1; (S)-4-(2-Chloro-6-(iodomethyl)pyrimidin-4-yl)-3-methylmorpholine hydrochloride (if applicable); (S)-4-(2-Chloro-6-(iodomethyl)-4-pyrimidinyl)-3-methylmorpholine HCl salt; (S)-4-(2-Chloro-6-(iodomethyl)pyrimidin-4-yl)-3-methylmorpholine HBr salt (if applicable)
EINECS	Contact for details

Quality Control

Our (S)-4-(2-Chloro-6-(Iodomethyl)Pyrimidin-4-Yl)-3-Methylmorpholine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.