Description

2-[5-(Chloromethyl)-1,2,4-Oxadiazol-3-Yl]Pyrimidine is a high-value heterocyclic building block and pharmaceutical intermediate of significant interest in modern synthetic chemistry. Its core structure, featuring both oxadiazole and pyrimidine rings with a reactive chloromethyl handle, makes it a versatile precursor for constructing complex molecules. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in oncology, antiviral, and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic scaffold for bioactivity.
• Chemical Biology Probe: Serves as a scaffold or linker in the design of molecular probes for studying biological pathways and target engagement.
• Material Science Precursor: Potential intermediate for creating specialized polymers or ligands with unique electronic or binding properties.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects.

Basic Information

Product Name	2-[5-(Chloromethyl)-1,2,4-Oxadiazol-3-Yl]Pyrimidine
CAS No.	1009562-63-3
Molecular Formula	C7H5ClN4O
Molecular Weight	196.59 g/mol
Synonyms	3-Pyrimidin-2-yl-5-(chloromethyl)-1,2,4-oxadiazole; 5-(Chloromethyl)-3-(pyrimidin-2-yl)-1,2,4-oxadiazole; 2-(5-(Chloromethyl)-1,2,4-oxadiazol-3-yl)pyrimidine; 1,2,4-Oxadiazole, 5-(chloromethyl)-3-(2-pyrimidinyl)-; Pyrimidine, 2-[5-(chloromethyl)-1,2,4-oxadiazol-3-yl]-; CAS 1009562-63-3
EINECS	Contact for details

Quality Control

Our 2-[5-(Chloromethyl)-1,2,4-Oxadiazol-3-Yl]Pyrimidine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment. We support cGMP (current Good Manufacturing Practice) standards for pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.