Description

(S)-4-(2,7-Dichloropyrido[2,3-D]Pyrimidin-4-Yl)-3-Methylmorpholine CAS NO 1009303-42-7 is a high-purity, chiral organic compound belonging to the pyridopyrimidine class, serving as a sophisticated building block in advanced pharmaceutical research and development. Its core value lies in its specific stereochemistry and functionalized heterocyclic structure, which is critical for modulating biological activity and pharmacokinetic properties in drug candidates. This intermediate is primarily needed by medicinal chemists and process development scientists in the pharmaceutical and biotechnology industries for the synthesis of targeted therapeutics.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel small-molecule drugs, particularly kinase inhibitors.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to optimize potency and selectivity of lead compounds.
• Process Chemistry: Serves as a critical intermediate in the scale-up and optimization of synthetic routes for active pharmaceutical ingredients (APIs).
• Oncology Drug Discovery: Employed in the synthesis of preclinical and clinical candidates targeting specific cancer pathways.
• Chemical Biology Probes: Utilized to develop selective chemical probes for studying enzyme function and cellular signaling.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs offering bespoke chemical synthesis services.

Basic Information

Product Name	(S)-4-(2,7-Dichloropyrido[2,3-D]Pyrimidin-4-Yl)-3-Methylmorpholine
CAS No.	1009303-42-7
Molecular Formula	C₁₄H₁₄Cl₂N₄O
Molecular Weight	325.19 g/mol
Synonyms	(S)-3-Methyl-4-(2,7-dichloropyrido[2,3-d]pyrimidin-4-yl)morpholine; (S)-4-(2,7-Dichloro-pyrido[2,3-d]pyrimidin-4-yl)-3-methyl-morpholine; (S)-4-(2,7-Dichloro-2,3-dihydro-1H-pyrido[2,3-d]pyrimidin-4-yl)-3-methylmorpholine; 1009303-42-7; (S)-enantiomer of 4-(2,7-dichloropyrido[2,3-d]pyrimidin-4-yl)-3-methylmorpholine; UNII-8J3Z5M55N6; 8J3Z5M55N6; BDBM50389335; AKOS025147064; ZINC000253909996
EINECS	Contact for details

Quality Control

Our (S)-4-(2,7-Dichloropyrido[2,3-D]Pyrimidin-4-Yl)-3-Methylmorpholine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral HPLC to ensure enantiomeric purity and identity confirmation by NMR and mass spectrometry. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, impurity profile, and other critical specifications to support your regulatory and research needs.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, well-ventilated area. The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere for long-term storage.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.