Description

2,2,3-Trifluoro-2,3-Dihydrobenzo[1,4]-Dioxin-5-Ol is a high-purity fluorinated benzodioxin derivative, serving as a critical advanced intermediate in modern synthetic chemistry. Its value lies in enabling the precise introduction of a trifluoromethylated dioxane moiety, which is instrumental for modulating the physicochemical and metabolic properties of target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients, particularly where enhanced bioavailability, stability, and lipophilicity are required.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially in central nervous system (CNS) and anti-infective therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides and fungicides, leveraging the fluorine atoms for improved efficacy and environmental profile.
• Material Science Precursor: Serves as a monomer or functionalizing agent in the development of specialty polymers and coatings with unique surface properties.
• Ligand and Catalyst Development: Employed in organometallic chemistry to create novel ligands for catalysis, particularly in asymmetric synthesis.
• Fluorine Chemistry Research: A valuable reagent for academic and industrial R&D focused on exploring new fluorination methodologies and fluorine-containing scaffolds.
• Liquid Crystal & OLED Materials: Potential intermediate for electronic chemicals used in display and lighting technologies due to its rigid, fluorinated structure.

Basic Information

Item	Details
Product Name	2,2,3-Trifluoro-2,3-Dihydrobenzo[1,4]-Dioxin-5-Ol
CAS No.	1008452-11-6
Molecular Formula	C9H5F3O3
Molecular Weight	218.13 g/mol
Synonyms	5-Hydroxy-2,2,3-trifluoro-2,3-dihydro-1,4-benzodioxine; 2,2,3-Trifluoro-2,3-dihydro-1,4-benzodioxin-5-ol; 1,4-Benzodioxin-5-ol, 2,2,3-trifluoro-2,3-dihydro-; Trifluorodihydrobenzodioxinol; TFBD-OH; Benzodioxol Fluorohydrin Derivative
EINECS	Contact for details

Quality Control

Our 2,2,3-Trifluoro-2,3-Dihydrobenzo[1,4]-Dioxin-5-Ol is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications and relevant industry standards for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.