Description

3-Fluoro-4-[(1-Methyl-1H-Pyrazol-4-Yl)Methoxy]Aniline is a high-purity, advanced pharmaceutical intermediate featuring a unique molecular scaffold combining an aniline core with a fluorinated methoxy-linked pyrazole moiety. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular interactions. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of next-generation small molecule drugs.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, especially kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its fluorinated aromatic structure for enhanced bioactivity and stability.
• Material Science: Serves as a precursor for functionalized polymers and advanced organic electronic materials due to its electron-donating aniline group and heterocyclic component.
• Chemical Synthesis: Acts as a versatile reagent for introducing the 3-fluoro-4-methoxyaniline pharmacophore into more complex molecular architectures.
• Life Science Research: Employed in biochemical assays and as a probe or ligand in medicinal chemistry programs for hit-to-lead optimization.

Basic Information

Product Name	3-Fluoro-4-[(1-Methyl-1H-Pyrazol-4-Yl)Methoxy]Aniline
CAS No.	1006960-98-0
Molecular Formula	C11H12FN3O
Molecular Weight	221.23 g/mol
Synonyms	3-Fluoro-4-[(1-methyl-1H-pyrazol-4-yl)methoxy]benzenamine; 4-[(1-Methyl-1H-pyrazol-4-yl)methoxy]-3-fluoroaniline; 3-Fluoro-4-((1-methyl-1H-pyrazol-4-yl)methoxy)aniline; 1006960-98-0; Benzenamine, 3-fluoro-4-[(1-methyl-1H-pyrazol-4-yl)methoxy]-; 3-Fluoro-4-(1-methyl-1H-pyrazol-4-ylmethoxy)aniline
EINECS	Contact for details

Quality Control

Our 3-Fluoro-4-[(1-Methyl-1H-Pyrazol-4-Yl)Methoxy]Aniline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment, ensuring full traceability and compliance with cGMP and ICH Q7 guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storage under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.