Description

4-(1-Methyl-1H-Pyrazol-4-Yl)Pyrimidine-2-Thiol is a high-value heterocyclic building block and key synthetic intermediate. This compound matters for its role in constructing complex molecular architectures, particularly in advanced pharmaceutical and agrochemical research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, particularly in kinase inhibitor research and other targeted therapies.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, leveraging its heterocyclic core for bioactivity.
• Chemical Research & Development: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Ligand and Catalyst Precursor: Potential use in the development of specialized ligands for catalysis or metal-organic frameworks (MOFs).
• Material Science Research: Investigated as a monomer or functional component in the development of advanced organic electronic materials.

Basic Information

Item	Detail
Product Name	4-(1-Methyl-1H-Pyrazol-4-Yl)Pyrimidine-2-Thiol
CAS No.	1006486-25-4
Molecular Formula	C8H8N4S
Molecular Weight	192.24 g/mol
Synonyms	2-Mercapto-4-(1-methyl-1H-pyrazol-4-yl)pyrimidine; 4-(1-Methyl-1H-pyrazol-4-yl)pyrimidine-2-thiol; 4-(1-Methyl-1H-pyrazol-4-yl)-2-pyrimidinethiol; 2-Pyrimidinethiol, 4-(1-methyl-1H-pyrazol-4-yl)-; 4-(1-Methylpyrazol-4-yl)pyrimidine-2-thiol
EINECS	Contact for details

Quality Control

Our 4-(1-Methyl-1H-Pyrazol-4-Yl)Pyrimidine-2-Thiol is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are available for every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended long-term storage temperature is 2-8°C. Allow the sealed container to reach ambient temperature before opening to minimize moisture ingress and oxidation.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.