Description

1-[4-Cyclopropyl-6-(Trifluoromethyl)Pyrimidin-2-Yl]-1H-Pyrazole-3-Carboxylic Acid CAS NO 1006448-08-3 is a high-purity, advanced pharmaceutical intermediate characterized by its unique pyrimidine-pyrazole hybrid structure. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in the development of targeted therapeutic agents. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for its role in creating molecules with specific biological activity.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of novel drug candidates, especially for targeted therapies.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides due to its bioactive pyrimidine core.
• Chemical Synthesis: Serves as a versatile precursor for creating complex heterocyclic compounds in medicinal chemistry.
• Life Science Research: Employed in biochemical and pharmacological studies to investigate structure-activity relationships (SAR).
• API Development: Integral to the process development and scale-up of new active pharmaceutical ingredients.

Basic Information

Product Name	1-[4-Cyclopropyl-6-(Trifluoromethyl)Pyrimidin-2-Yl]-1H-Pyrazole-3-Carboxylic Acid
CAS No.	1006448-08-3
Molecular Formula	C12H9F3N4O2
Molecular Weight	298.22 g/mol
Synonyms	1-[4-Cyclopropyl-6-(trifluoromethyl)pyrimidin-2-yl]-1H-pyrazole-3-carboxylic acid; 1H-Pyrazole-3-carboxylic acid, 1-[4-cyclopropyl-6-(trifluoromethyl)-2-pyrimidinyl]-; 1-(4-Cyclopropyl-6-(trifluoromethyl)pyrimidin-2-yl)-1H-pyrazole-3-carboxylic acid; 1006448-08-3; CAS 1006448-08-3
EINECS	Contact for details

Quality Control

Our 1-[4-Cyclopropyl-6-(Trifluoromethyl)Pyrimidin-2-Yl]-1H-Pyrazole-3-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.