Description

{[4-(1-Methyl-1H-Pyrazol-4-Yl)-6-(Trifluoromethyl)Pyrimidin-2-Yl]Sulfanyl}Acetic Acid is a high-value, multifunctional heterocyclic building block designed for advanced chemical synthesis. Its core value lies in its unique molecular architecture, which combines a pyrimidine core with a pyrazole substituent and a reactive thioacetic acid moiety, enabling precise molecular modifications. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries seeking to develop novel active ingredients with enhanced properties.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in kinase inhibitor programs and other small-molecule therapeutics.
• Agrochemical Synthesis: Serves as a critical precursor in the creation of next-generation herbicides, fungicides, and insecticides, leveraging the bioactivity of the pyrimidine and pyrazole motifs.
• Chemical Research & Development: Used as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Material Science: Potential applications in the synthesis of specialty polymers, ligands for catalysis, or advanced organic electronic materials due to its conjugated system.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of complex target molecules on a commercial scale.

Basic Information

Product Name	{[4-(1-Methyl-1H-Pyrazol-4-Yl)-6-(Trifluoromethyl)Pyrimidin-2-Yl]Sulfanyl}Acetic Acid
CAS No.	1006440-64-7
Molecular Formula	C11H9F3N4O2S
Molecular Weight	318.27 g/mol
Synonyms	2-({[4-(1-Methyl-1H-pyrazol-4-yl)-6-(trifluoromethyl)pyrimidin-2-yl]sulfanyl})acetic acid; [4-(1-Methyl-1H-pyrazol-4-yl)-6-(trifluoromethyl)pyrimidin-2-yl]sulfanylacetic acid; 2-[[4-(1-Methylpyrazol-4-yl)-6-(trifluoromethyl)pyrimidin-2-yl]thio]acetic acid; Acetic acid, 2-[[4-(1-methyl-1H-pyrazol-4-yl)-6-(trifluoromethyl)-2-pyrimidinyl]thio]-; (4-(1-Methyl-1H-pyrazol-4-yl)-6-(trifluoromethyl)pyrimidin-2-ylthio)acetic acid
EINECS	Contact for details

Quality Control

Our {[4-(1-Methyl-1H-Pyrazol-4-Yl)-6-(Trifluoromethyl)Pyrimidin-2-Yl]Sulfanyl}Acetic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for pharmaceutical and agrochemical applications. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This compound may be moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/IR)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.