Description

1-[4-(1,3-Dimethyl-1H-Pyrazol-4-Yl)-6-(Trifluoromethyl)Pyrimidin-2-Yl]Piperidine-4-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of novel active ingredients. This compound is critical for research and development in medicinal chemistry, offering a versatile scaffold for creating targeted therapeutics. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing new drug candidates, particularly in oncology and other therapeutic areas.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel small-molecule drug candidates.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic targets.
• API Development: Serves as a precursor in the development of Active Pharmaceutical Ingredients (APIs), especially those targeting kinase inhibition.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for the pharmaceutical industry.
• Academic Research: Utilized in university and institutional labs for chemical biology and drug discovery projects.
• Preclinical Development: Employed in the production of compounds for pharmacological and toxicological evaluation.

Basic Information

Product Name	1-[4-(1,3-Dimethyl-1H-Pyrazol-4-Yl)-6-(Trifluoromethyl)Pyrimidin-2-Yl]Piperidine-4-Carboxylic Acid
CAS No.	1006334-19-5
Molecular Formula	C16H18F3N5O2
Molecular Weight	369.34 g/mol
Synonyms	1-[4-(1,3-Dimethyl-1H-pyrazol-4-yl)-6-(trifluoromethyl)pyrimidin-2-yl]piperidine-4-carboxylic acid; 4-Piperidinecarboxylic acid, 1-[4-(1,3-dimethyl-1H-pyrazol-4-yl)-6-(trifluoromethyl)-2-pyrimidinyl]-; 1006334-19-5; 1-(4-(1,3-dimethyl-1H-pyrazol-4-yl)-6-(trifluoromethyl)pyrimidin-2-yl)piperidine-4-carboxylic acid; 1-[4-(1,3-Dimethyl-1H-pyrazol-4-yl)-6-(trifluoromethyl)pyrimidin-2-yl]piperidine-4-carboxylic acid; Piperidine-4-carboxylic acid, 1-[4-(1,3-dimethyl-1H-pyrazol-4-yl)-6-(trifluoromethyl)-2-pyrimidinyl]-
EINECS	Contact for details

Quality Control

Our 1-[4-(1,3-Dimethyl-1H-Pyrazol-4-Yl)-6-(Trifluoromethyl)Pyrimidin-2-Yl]Piperidine-4-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This material is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere if necessary to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any single impurity ≤ 0.5% Total impurities ≤ 1.5%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.