Description

4-Hydroxy-6-[5-(2-Nitrophenyl)Furan-2-Yl]-5-(Phenylcarbonyl)-4-(Trifluoromethyl)Tetrahydropyrimidin-2(1H)-One is a high-value, structurally complex heterocyclic compound featuring a tetrahydropyrimidinone core. This molecule is of significant interest for its potential as a key synthetic intermediate or a pharmacologically active scaffold in advanced research and development. It is primarily sought by pharmaceutical R&D and fine chemical synthesis sectors for developing novel therapeutic agents and specialty chemicals.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel drug candidates, particularly those targeting specific enzymatic pathways.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and high-throughput screening libraries.
• Organic Synthesis: Acts as a versatile precursor for constructing complex polycyclic frameworks due to its multiple functional handles.
• Agrochemical Development: Investigated for potential application in creating new active ingredients for crop protection.
• Chemical Biology Probes: Utilized in the development of molecular probes to study biological processes and protein interactions.
• Academic & Institutional Research: Employed in universities and research institutes for fundamental studies in heterocyclic and fluorine chemistry.

Basic Information

Product Name	4-Hydroxy-6-[5-(2-Nitrophenyl)Furan-2-Yl]-5-(Phenylcarbonyl)-4-(Trifluoromethyl)Tetrahydropyrimidin-2(1H)-One
CAS No.	1005280-47-6
Molecular Formula	C22H14F3N3O6
Molecular Weight	473.36 g/mol
Synonyms	4-(Trifluoromethyl)-4-hydroxy-5-benzoyl-6-[5-(2-nitrophenyl)-2-furyl]-1,4,5,6-tetrahydropyrimidin-2(1H)-one; 4-Hydroxy-6-[5-(2-nitrophenyl)-2-furyl]-5-benzoyl-4-(trifluoromethyl)-1,4,5,6-tetrahydropyrimidin-2(1H)-one; 4-Hydroxy-6-(5-(2-nitrophenyl)furan-2-yl)-5-(phenylcarbonyl)-4-(trifluoromethyl)-1,4,5,6-tetrahydropyrimidin-2(1H)-one; 4-Hydroxy-6-[5-(2-nitrophenyl)furan-2-yl]-5-(phenylcarbonyl)-4-(trifluoromethyl)-1,4,5,6-tetrahydropyrimidin-2(1H)-one; 4-Hydroxy-6-[5-(2-nitrophenyl)furan-2-yl]-5-(phenylcarbonyl)-4-(trifluoromethyl)tetrahydropyrimidin-2(1H)-one
EINECS	Contact for details

Quality Control

Our 4-Hydroxy-6-[5-(2-Nitrophenyl)Furan-2-Yl]-5-(Phenylcarbonyl)-4-(Trifluoromethyl)Tetrahydropyrimidin-2(1H)-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity (typically by HPLC), identity confirmation (IR, NMR), and impurity profiles is provided with every shipment to support your research and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials and sources of ignition. For long-term storage, consider storing under an inert atmosphere to ensure maximum stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.