Description

Methyl 6-Chloropyrazolo[1,5-A]Pyrimidine-2-Carboxylate is a high-purity heterocyclic building block of significant importance in modern organic synthesis. This compound serves as a critical intermediate for the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly in kinase inhibitor research and other small-molecule therapeutics.
• Agrochemical Development: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging its pyrazolopyrimidine core.
• Material Science Research: Employed as a building block for creating novel organic electronic materials or metal-organic frameworks (MOFs).
• Chemical Biology Probes: Serves as a scaffold for developing molecular probes to study biological pathways and enzyme functions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring specialized heterocycles.

Basic Information

Product Name	Methyl 6-Chloropyrazolo[1,5-A]Pyrimidine-2-Carboxylate
CAS No.	1005209-41-5
Molecular Formula	C8H6ClN3O2
Molecular Weight	211.61 g/mol
Synonyms	Methyl 6-chloro-1H-pyrazolo[1,5-a]pyrimidine-2-carboxylate; 6-Chloro-1H-pyrazolo[1,5-a]pyrimidine-2-carboxylic acid methyl ester; Methyl 6-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate; 1H-Pyrazolo[1,5-a]pyrimidine-2-carboxylic acid, 6-chloro-, methyl ester; 6-Chloro-1H-pyrazolo[1,5-a]pyrimidine-2-carboxylate methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 6-Chloropyrazolo[1,5-A]Pyrimidine-2-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specification results. Our quality commitment ensures the material meets the high standards required for research and commercial synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.