Description

4-(1,3-Dimethyl-1H-Pyrazol-4-Yl)-2-Hydrazinyl-6-(Trifluoromethyl)Pyrimidine is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of novel active ingredients. This compound is valued for its unique heterocyclic structure, which incorporates a pyrazole and a trifluoromethyl-substituted pyrimidine ring, offering a versatile scaffold for medicinal chemistry research and development. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries seeking to develop new therapeutic agents and crop protection solutions.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of novel drug candidates, particularly in oncology, antiviral, and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Serves as a precursor in the development of new pesticides and herbicides, leveraging the biological activity of the pyrimidine and pyrazole motifs.
• Chemical Biology Probe: Used in academic and industrial research to study enzyme inhibition and protein-ligand interactions due to its hydrazinyl functional group.
• Material Science Research: Investigated as a potential monomer or additive for creating specialty polymers with specific electronic or thermal properties.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects requiring high-purity, complex heterocycles.

Basic Information

Product Name	4-(1,3-Dimethyl-1H-Pyrazol-4-Yl)-2-Hydrazinyl-6-(Trifluoromethyl)Pyrimidine
CAS No.	1004644-03-4
Molecular Formula	C10H11F3N6
Molecular Weight	272.23 g/mol
Synonyms	2-Hydrazinyl-4-(1,3-dimethyl-1H-pyrazol-4-yl)-6-(trifluoromethyl)pyrimidine; 4-(1,3-Dimethylpyrazol-4-yl)-2-hydrazino-6-trifluoromethylpyrimidine; 6-(Trifluoromethyl)-4-(1,3-dimethyl-1H-pyrazol-4-yl)pyrimidine-2-hydrazine; 1004644-03-4; 4-(1,3-Dimethyl-1H-pyrazol-4-yl)-2-hydrozinyl-6-(trifluoromethyl)pyrimidine
EINECS	Contact for details

Quality Control

Our production of 4-(1,3-Dimethyl-1H-Pyrazol-4-Yl)-2-Hydrazinyl-6-(Trifluoromethyl)Pyrimidine adheres to stringent quality management protocols to ensure batch-to-batch consistency and reliability for your critical R&D and scale-up processes. All materials undergo rigorous analytical testing, including HPLC, NMR, and MS, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, long-term storage under an inert atmosphere (e.g., nitrogen or argon) is recommended for optimal stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.