Description

2-Methyl-2-[4-(Trifluoromethyl)Phenyl]Propan-1-Amine is a high-purity, functionalized amine building block featuring a sterically hindered structure and a trifluoromethylphenyl group. This compound is valued for its role in modulating the physicochemical properties of target molecules, particularly in enhancing metabolic stability and lipophilicity. It is primarily sought by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: A key building block for the research and synthesis of new chemical entities (NCEs), particularly in developing candidates for central nervous system (CNS) and metabolic disease targets.
• Agrochemical Synthesis: Used in creating advanced intermediates for novel herbicides, fungicides, and insecticides, where the trifluoromethyl group can improve biological activity and environmental stability.
• Ligand & Catalyst Development: Serves as a precursor for designing specialized ligands in asymmetric catalysis and organometallic chemistry due to its bulky, electron-deficient aromatic system.
• Material Science Research: Employed in the development of specialty polymers, resins, and advanced organic frameworks where its unique structure can impart specific thermal or chemical resistance properties.
• Life Science Reagents: Utilized in the preparation of biochemical probes, fluorescent markers, and other research tools where a stable, hydrophobic amine handle is required.

Basic Information

Product Name	2-Methyl-2-[4-(Trifluoromethyl)Phenyl]Propan-1-Amine
CAS No.	1004282-76-1
Molecular Formula	C11H14F3N
Molecular Weight	217.23 g/mol
Synonyms	1-Propanamine, 2-methyl-2-[4-(trifluoromethyl)phenyl]-; 2-Methyl-2-(4-trifluoromethylphenyl)propan-1-amine; α,α-Dimethyl-4-(trifluoromethyl)benzeneethanamine; 4-(Trifluoromethyl)neopentylamine; 2-(4-Trifluoromethylphenyl)-2-methylpropylamine; 2-Methyl-2-(4-trifluoromethylphenyl)-1-propylamine
EINECS	Contact for details

Quality Control

Every batch of 2-Methyl-2-[4-(Trifluoromethyl)Phenyl]Propan-1-Amine is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the product meets the high-purity standards required for research and commercial synthesis. A detailed Certificate of Analysis (COA), including results from HPLC, NMR, and GC-MS, is supplied with each shipment to guarantee identity, purity, and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.