Description

4-(Difluoromethoxy)-2-Fluoroaniline (Wxfc0706) is a specialized fluorinated aniline derivative, a key building block in advanced organic synthesis. This compound matters for its role as a crucial intermediate in the development of active pharmaceutical ingredients (APIs) and agrochemicals, where its unique difluoromethoxy and fluoro substituents impart desirable metabolic stability and bioavailability. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to innovate new compounds with enhanced properties. Consistent quality and reliable supply of this high-value intermediate are critical for streamlining complex synthesis pathways.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in therapeutic areas requiring fluorinated motifs for improved efficacy and pharmacokinetics.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine atoms enhance biological activity and environmental stability.
• Liquid Crystal Materials: Serves as a building block for fluorinated aromatic components in electronic display technologies.
• Organic Light-Emitting Diodes (OLEDs): Employed in the development of electron-transport or emissive layer materials for high-performance displays.
• Advanced Polymer Chemistry: Acts as a monomer or modifier for creating specialty polymers with specific thermal, chemical, or surface properties.
• Chemical Research & Development: A versatile reagent for exploring new fluorination methodologies and constructing complex molecular architectures in academic and industrial labs.

Basic Information

Item	Detail
Product Name	4-(Difluoromethoxy)-2-Fluoroaniline (Wxfc0706)
CAS No.	1003865-65-3
Molecular Formula	C7H6F3NO
Molecular Weight	177.12 g/mol
Synonyms	2-Fluoro-4-(difluoromethoxy)aniline; 4-(Difluoromethoxy)-2-fluoro-benzenamine; 2-Fluoro-4-(difluoromethoxy)phenylamine; WXFC0706; Aniline, 4-(difluoromethoxy)-2-fluoro-; 1003865-65-3; 2-Fluoro-4-difluoromethoxyaniline
EINECS	Contact for details

Quality Control

Our 4-(Difluoromethoxy)-2-Fluoroaniline is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency suitable for demanding synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing identity, assay, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, ensuring reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Light yellow to brown crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.